BAIT
ODF2
AI848335, MMTEST29, RP23-443G7.4
outer dense fiber of sperm tails 2
GO Process (1)
GO Function (2)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Mus musculus
PREY
ROCK1
P160Rock, ROCK-I, Ac2-154
Rho-associated coiled-coil containing protein kinase 1
GO Process (15)
GO Function (2)
GO Component (4)
Gene Ontology Biological Process
- Rho protein signal transduction [IMP]
- actin cytoskeleton organization [ISO]
- apical constriction [ISO]
- bleb assembly [ISO]
- cytoskeleton organization [IMP]
- leukocyte cell-cell adhesion [ISO]
- leukocyte migration [ISO]
- leukocyte tethering or rolling [ISO]
- membrane to membrane docking [ISO]
- myoblast migration [ISO, ISS]
- negative regulation of angiogenesis [ISO]
- negative regulation of neuron apoptotic process [ISO]
- positive regulation of focal adhesion assembly [ISO, ISS]
- regulation of actin filament-based process [ISO]
- regulation of keratinocyte differentiation [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- cytoskeleton [ISO, ISS]
- lamellipodium [ISO, ISS]
- plasma membrane [ISO, ISS]
- ruffle [ISO, ISS]
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
The novel testicular enrichment protein Cfap58 is required for Notch-associated ciliogenesis.
Cilia and flagella are critical organelles with conserved internal structures and diverse developmental and physiological processes according to cell type. Although the core components of structures are shared with thousands of associated proteins involved in cilia or flagella formation, we hypothesized that some unknown proteins, such as outer dense fiber 2 (Odf2/Cenexin) perform distinct functions in these organelles. In the ... [more]
Biosci Rep Dec. 31, 2019; 40(1); [Pubmed: 31904090]
Throughput
- High Throughput
Curated By
- BioGRID