BAIT
NINL
NLP, dJ691N24.1, RP4-691N24.1
ninein-like
GO Process (2)
GO Function (0)
GO Component (1)
Gene Ontology Biological Process
Homo sapiens
PREY
MYO5A
GS1, MYH12, MYO5, MYR12
myosin VA (heavy chain 12, myoxin)
GO Process (10)
GO Function (3)
GO Component (17)
Gene Ontology Biological Process
- actin filament-based movement [NAS]
- cellular protein metabolic process [TAS]
- cellular response to insulin stimulus [ISS]
- membrane organization [TAS]
- post-Golgi vesicle-mediated transport [IMP]
- protein localization to plasma membrane [ISS]
- regulation of Golgi organization [IMP]
- transport [NAS]
- vesicle transport along actin filament [IMP]
- vesicle-mediated transport [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- actin filament [IDA]
- cytoplasm [IDA]
- cytosol [IDA]
- early endosome [IDA]
- endoplasmic reticulum [IDA]
- extracellular vesicular exosome [IDA]
- filopodium tip [IDA]
- growth cone [NAS]
- insulin-responsive compartment [ISS]
- late endosome [IDA]
- lysosome [IDA]
- membrane [IDA]
- neuron projection [NAS]
- peroxisome [IDA]
- recycling endosome [IDA]
- ruffle [IDA]
- vesicle [IDA]
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
The Ciliopathy Protein CC2D2A Associates with NINL and Functions in RAB8-MICAL3-Regulated Vesicle Trafficking.
Ciliopathies are a group of human disorders caused by dysfunction of primary cilia, ubiquitous microtubule-based organelles involved in transduction of extra-cellular signals to the cell. This function requires the concentration of receptors and channels in the ciliary membrane, which is achieved by complex trafficking mechanisms, in part controlled by the small GTPase RAB8, and by sorting at the transition zone ... [more]
PLoS Genet Oct. 01, 2015; 11(10);e1005575 [Pubmed: 26485645]
Throughput
- High Throughput
Curated By
- BioGRID