BAIT
AKT3
Pkbg
v-akt murine thymoma viral oncogene homolog 3
GO Process (5)
GO Function (3)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
GLUL
Glns
glutamate-ammonia ligase
GO Process (11)
GO Function (7)
GO Component (14)
Gene Ontology Biological Process
- ammonia assimilation cycle [IDA, TAS]
- cell proliferation [ISO]
- cellular response to starvation [ISO]
- glutamate metabolic process [IDA]
- glutamine biosynthetic process [IDA]
- neurotransmitter metabolic process [TAS]
- positive regulation of epithelial cell proliferation [IMP]
- positive regulation of insulin secretion [IMP]
- positive regulation of synaptic transmission, glutamatergic [IMP]
- protein homooligomerization [IDA]
- response to glucose [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- axon terminus [IDA]
- cell body [ISO]
- cell projection [IDA]
- cytoplasm [IDA, ISO]
- extracellular vesicular exosome [ISO]
- glial cell projection [ISO]
- intracellular membrane-bounded organelle [IDA]
- mitochondrion [ISO]
- myelin sheath [ISO]
- neuron projection [IDA]
- nucleus [ISO]
- perikaryon [IDA]
- protein complex [IDA]
- rough endoplasmic reticulum [IDA]
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Structural Analysis of Hippocampal Kinase Signal Transduction.
Kinases are a major clinical target for human diseases. Identifying the proteins that interact with kinases in vivo will provide information on unreported substrates and will potentially lead to more specific methods for therapeutic kinase regulation. Here, endogenous immunoprecipitations of evolutionally distinct kinases (i.e., Akt, ERK2, and CAMK2) from rodent hippocampi were analyzed by mass spectrometry to generate three highly ... [more]
ACS Chem Neurosci Dec. 19, 2017; 9(12);3072-3085 [Pubmed: 30053369]
Throughput
- Low Throughput
Curated By
- BioGRID