BAIT
AKT3
Pkbg
v-akt murine thymoma viral oncogene homolog 3
GO Process (5)
GO Function (3)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
NCKAP1
NCK-associated protein 1
GO Process (23)
GO Function (3)
GO Component (4)
Gene Ontology Biological Process
- Rac protein signal transduction [ISO]
- apical protein localization [ISO]
- basal protein localization [ISO]
- cell migration involved in gastrulation [ISO]
- embryonic body morphogenesis [ISO]
- embryonic foregut morphogenesis [ISO]
- embryonic heart tube development [ISO]
- endoderm development [ISO]
- establishment or maintenance of actin cytoskeleton polarity [ISO]
- in utero embryonic development [ISO]
- lamellipodium assembly [ISO]
- mesodermal cell migration [ISO]
- neural tube closure [ISO]
- notochord development [ISO]
- notochord morphogenesis [ISO]
- paraxial mesoderm development [ISO]
- paraxial mesoderm morphogenesis [ISO]
- positive regulation of Arp2/3 complex-mediated actin nucleation [ISO]
- positive regulation of lamellipodium assembly [ISO]
- protein stabilization [ISO]
- regulation of protein localization [ISO]
- somitogenesis [ISO]
- zygotic determination of anterior/posterior axis, embryo [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Structural Analysis of Hippocampal Kinase Signal Transduction.
Kinases are a major clinical target for human diseases. Identifying the proteins that interact with kinases in vivo will provide information on unreported substrates and will potentially lead to more specific methods for therapeutic kinase regulation. Here, endogenous immunoprecipitations of evolutionally distinct kinases (i.e., Akt, ERK2, and CAMK2) from rodent hippocampi were analyzed by mass spectrometry to generate three highly ... [more]
ACS Chem Neurosci Dec. 19, 2017; 9(12);3072-3085 [Pubmed: 30053369]
Throughput
- Low Throughput
Curated By
- BioGRID