BAIT
AKT3
Pkbg
v-akt murine thymoma viral oncogene homolog 3
GO Process (5)
GO Function (3)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
PPP5C
protein phosphatase 5, catalytic subunit
GO Process (15)
GO Function (7)
GO Component (10)
Gene Ontology Biological Process
- cellular response to cadmium ion [IEP]
- cellular response to hydrogen peroxide [IEP]
- dephosphorylation [ISO]
- histone dephosphorylation [IDA]
- negative regulation of cell death [IMP]
- negative regulation of neuron death [IMP]
- negative regulation of protein phosphorylation [IMP]
- positive regulation of I-kappaB kinase/NF-kappaB signaling [ISO]
- positive regulation of glucocorticoid receptor signaling pathway [IMP]
- protein dephosphorylation [IDA, IMP]
- protein heterooligomerization [IPI]
- protein oligomerization [IDA]
- response to lead ion [IEP]
- response to morphine [ISO]
- signal transduction [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Structural Analysis of Hippocampal Kinase Signal Transduction.
Kinases are a major clinical target for human diseases. Identifying the proteins that interact with kinases in vivo will provide information on unreported substrates and will potentially lead to more specific methods for therapeutic kinase regulation. Here, endogenous immunoprecipitations of evolutionally distinct kinases (i.e., Akt, ERK2, and CAMK2) from rodent hippocampi were analyzed by mass spectrometry to generate three highly ... [more]
ACS Chem Neurosci Dec. 19, 2017; 9(12);3072-3085 [Pubmed: 30053369]
Throughput
- Low Throughput
Curated By
- BioGRID