BAIT
AKT3
Pkbg
v-akt murine thymoma viral oncogene homolog 3
GO Process (5)
GO Function (3)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
SNX1
sorting nexin 1
GO Process (9)
GO Function (6)
GO Component (11)
Gene Ontology Biological Process
- early endosome to Golgi transport [IBA, ISO]
- endocytosis [IBA]
- endosomal transport [IEP]
- intracellular protein transport [ISO]
- lamellipodium morphogenesis [ISO, ISS]
- positive regulation of protein catabolic process [IMP]
- receptor internalization [ISO, ISS]
- retrograde transport, endosome to Golgi [ISO, ISS]
- vesicle organization [IBA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Structural Analysis of Hippocampal Kinase Signal Transduction.
Kinases are a major clinical target for human diseases. Identifying the proteins that interact with kinases in vivo will provide information on unreported substrates and will potentially lead to more specific methods for therapeutic kinase regulation. Here, endogenous immunoprecipitations of evolutionally distinct kinases (i.e., Akt, ERK2, and CAMK2) from rodent hippocampi were analyzed by mass spectrometry to generate three highly ... [more]
ACS Chem Neurosci Dec. 19, 2017; 9(12);3072-3085 [Pubmed: 30053369]
Throughput
- Low Throughput
Curated By
- BioGRID