B3GAT3
Gene Ontology Biological Process
- carbohydrate metabolic process [TAS]
- chondroitin sulfate metabolic process [TAS]
- chondroitin sulfate proteoglycan biosynthetic process [IDA]
- dermatan sulfate proteoglycan biosynthetic process [IDA]
- glycosaminoglycan biosynthetic process [IDA, NAS]
- glycosaminoglycan metabolic process [TAS]
- heparan sulfate proteoglycan biosynthetic process [IDA]
- positive regulation of catalytic activity [IDA]
- positive regulation of intracellular protein transport [IMP]
- small molecule metabolic process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
B3GAT3
Gene Ontology Biological Process
- carbohydrate metabolic process [TAS]
- chondroitin sulfate metabolic process [TAS]
- chondroitin sulfate proteoglycan biosynthetic process [IDA]
- dermatan sulfate proteoglycan biosynthetic process [IDA]
- glycosaminoglycan biosynthetic process [IDA, NAS]
- glycosaminoglycan metabolic process [TAS]
- heparan sulfate proteoglycan biosynthetic process [IDA]
- positive regulation of catalytic activity [IDA]
- positive regulation of intracellular protein transport [IMP]
- small molecule metabolic process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Reconstituted Complex
An interaction is inferred between proteins in vitro. This can include proteins in recombinant form or proteins isolated directly from cells with recombinant or purified bait. For example, GST pull-down assays where a GST-tagged protein is first isolated and then used to fish interactors from cell lysates are considered reconstituted complexes (e.g. PUBMED: 14657240, Fig. 4A or PUBMED: 14761940, Fig. 5). This can also include gel-shifts, surface plasmon resonance, isothermal titration calorimetry (ITC) and bio-layer interferometry (BLI) experiments. The bait-hit directionality may not be clear for 2 interacting proteins. In these cases the directionality is up to the discretion of the curator.
Publication
Structure/function of the human Ga1beta1,3-glucuronosyltransferase. Dimerization and functional activity are mediated by two crucial cysteine residues.
Galbeta1,3-glucuronosyltransferase (GlcAT-I) that catalyzes the transfer of a glucuronic acid residue onto the trisaccharide primer of the glycosaminoglycan-protein linkage region plays an essential role in the early steps of the biosynthesis of glycosaminoglycans. In order to gain insight into the structure/function of the enzyme, the human recombinant GlcAT-I was successfully expressed in the yeast Pichia pastoris, with an apparent molecular ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID