CNTNAP2
Gene Ontology Biological Process
- adult behavior [IMP]
- brain development [TAS]
- cellular protein localization [ISS]
- cerebral cortex development [IEP]
- clustering of voltage-gated potassium channels [ISS]
- learning [IMP]
- limbic system development [IEP]
- neuron projection development [ISS]
- neuron recognition [NAS]
- protein localization to juxtaparanode region of axon [ISS]
- social behavior [IMP]
- striatum development [IEP]
- superior temporal gyrus development [IEP]
- thalamus development [IEP]
- transmission of nerve impulse [NAS]
- vocalization behavior [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
CASK
Gene Ontology Biological Process
- cell adhesion [TAS]
- extracellular matrix organization [TAS]
- negative regulation of cell-matrix adhesion [IMP]
- negative regulation of cellular response to growth factor stimulus [IMP]
- negative regulation of keratinocyte proliferation [IMP]
- negative regulation of wound healing [IMP]
- nucleotide phosphorylation [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Reconstituted Complex
An interaction is inferred between proteins in vitro. This can include proteins in recombinant form or proteins isolated directly from cells with recombinant or purified bait. For example, GST pull-down assays where a GST-tagged protein is first isolated and then used to fish interactors from cell lysates are considered reconstituted complexes (e.g. PUBMED: 14657240, Fig. 4A or PUBMED: 14761940, Fig. 5). This can also include gel-shifts, surface plasmon resonance, isothermal titration calorimetry (ITC) and bio-layer interferometry (BLI) experiments. The bait-hit directionality may not be clear for 2 interacting proteins. In these cases the directionality is up to the discretion of the curator.
Publication
Caspr3 and caspr4, two novel members of the caspr family are expressed in the nervous system and interact with PDZ domains.
The NCP family of cell-recognition molecules represents a distinct subgroup of the neurexins that includes Caspr and Caspr2, as well as Drosophila Neurexin-IV and axotactin. Here, we report the identification of Caspr3 and Caspr4, two new NCPs expressed in nervous system. Caspr3 was detected along axons in the corpus callosum, spinal cord, basket cells in the cerebellum and in peripheral ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID