BAIT
RGL2
HKE1.5, KE1.5, RAB2L, DADB-159G18.6
ral guanine nucleotide dissociation stimulator-like 2
GO Process (2)
GO Function (1)
GO Component (0)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
PREY
RALA
RAL
v-ral simian leukemia viral oncogene homolog A (ras related)
GO Process (10)
GO Function (2)
GO Component (7)
Gene Ontology Biological Process
- Ras protein signal transduction [TAS]
- actin cytoskeleton reorganization [IDA]
- chemotaxis [TAS]
- cytokinesis [IDA]
- membrane organization [TAS]
- membrane raft localization [IDA]
- neurotrophin TRK receptor signaling pathway [TAS]
- positive regulation of filopodium assembly [IDA]
- regulation of exocytosis [IDA]
- signal transduction [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Identification of a novel RalGDS-related protein as a candidate effector for Ras and Rap1.
Although Ras and Rap1 share interaction with common candidate effector proteins, Rap1 lacks the transforming activity exhibited by Ras proteins. It has been speculated that Rap antagonizes Ras transformation through the formation of nonproductive complexes with critical Ras effector targets. To understand further the distinct biological functions of these two closely related proteins, we searched for Rap1b-binding proteins by yeast ... [more]
J. Biol. Chem. Nov. 22, 1996; 271(47);29903-8 [Pubmed: 8939933]
Throughput
- Low Throughput
Curated By
- BioGRID