BAIT
MYSM1
2A-DUB, 2ADUB, RP4-592A1.1
Myb-like, SWIRM and MPN domains 1
GO Process (3)
GO Function (6)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
PPIB
CYP-S1, CYPB, HEL-S-39, OI9, SCYLP
peptidylprolyl isomerase B (cyclophilin B)
GO Process (7)
GO Function (6)
GO Component (7)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Interaction of Deubiquitinase 2A-DUB/MYSM1 with DNA Repair and Replication Factors.
The deubiquitination of histone H2A on lysine 119 by 2A-DUB/MYSM1, BAP1, USP16, and other enzymes is required for key cellular processes, including transcriptional activation, apoptosis, and cell cycle control, during normal hematopoiesis and tissue development, and in tumor cells. Based on our finding that MYSM1 colocalizes with ?H2AX foci in human peripheral blood mononuclear cells, leukemia cells, and melanoma cells ... [more]
Int J Mol Sci May. 26, 2020; 21(11); [Pubmed: 32466590]
Throughput
- High Throughput
Additional Notes
- assayed using SCX-HPLC MS/MS (tandem mass spectrometry)
Curated By
- BioGRID