Reconstituted Complex

An interaction is detected between purified proteins in vitro.

Publication

Nuclear NonO/p54(nrb) protein is a nonclassical carbonic anhydrase.

Karhumaa P, Parkkila S, Waheed A, Parkkila AK, Kaunisto K, Tucker PW, Huang CJ, Sly WS, Rajaniemi H

The growing carbonic anhydrase (CA) gene family includes 11 enzymatically active isozymes in mammals. Each of them has a characteristic cellular and subcellular distribution pattern. In this report, we demonstrate for the first time a nuclear protein with CA activity. A polypeptide recognized by CA II antibodies was purified from several rat tissues using CA inhibitor affinity chromatography. This polypeptide ... [more]

J. Biol. Chem. May. 26, 2000; 275(21);16044-9 [Pubmed: 10821857]

Throughput

  • Low Throughput

Curated By

  • BioGRID