BAIT
FNDC5
1500001L03Rik, AI836596, C87088, PeP, Pxp, RP23-284L6.4
fibronectin type III domain containing 5
GO Process (2)
GO Function (1)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
CD44
AU023126, AW121933, AW146109, HERMES, Ly-24, Pgp-1, RP23-203N8.3
CD44 antigen
GO Process (25)
GO Function (8)
GO Component (12)
Gene Ontology Biological Process
- Wnt signaling pathway [IDA]
- branching involved in prostate gland morphogenesis [IMP]
- branching involved in ureteric bud morphogenesis [IMP]
- cell adhesion [IDA, ISO]
- cell migration [ISO]
- cellular response to fibroblast growth factor stimulus [ISO]
- hyaluronan catabolic process [ISO]
- macrophage fusion [ISO]
- monocyte aggregation [ISO]
- negative regulation of DNA damage response, signal transduction by p53 class mediator [IMP, ISO]
- negative regulation of apoptotic process [ISO]
- negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [ISO]
- negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [IMP, ISO]
- negative regulation of mature B cell apoptotic process [IDA]
- neuron projection development [ISO]
- positive regulation of ERK1 and ERK2 cascade [IMP, ISO]
- positive regulation of adaptive immune response [NAS]
- positive regulation of gene expression [IGI]
- positive regulation of heterotypic cell-cell adhesion [ISO]
- positive regulation of monocyte aggregation [ISO]
- positive regulation of neutrophil apoptotic process [ISO]
- positive regulation of peptidyl-serine phosphorylation [IMP, ISO]
- positive regulation of peptidyl-tyrosine phosphorylation [IMP, ISO]
- regulation of cell growth [ISO]
- wound healing involved in inflammatory response [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- Golgi apparatus [ISO]
- apical plasma membrane [ISO]
- basolateral plasma membrane [IDA, ISO]
- cell surface [IDA, ISO]
- cytoplasm [ISO]
- external side of plasma membrane [IDA]
- extracellular vesicular exosome [ISO]
- focal adhesion [ISO]
- macrophage migration inhibitory factor receptor complex [IDA, ISO]
- nucleus [ISO]
- plasma membrane [IDA, ISO]
- protein complex [ISO]
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Irisin Mediates Effects on Bone and Fat via ?V Integrin Receptors.
Irisin is secreted by muscle, increases with exercise, and mediates certain favorable effects of physical activity. In particular, irisin has been shown to have beneficial effects in adipose tissues, brain, and bone. However, the skeletal response to exercise is less clear, and the receptor for irisin has not been identified. Here we show that irisin binds to proteins of the ... [more]
Cell Dec. 13, 2017; 175(7);1756-1768.e17 [Pubmed: 30550785]
Throughput
- High Throughput
Curated By
- BioGRID