BAIT
CFD
Adn, DF
complement factor D (adipsin)
GO Process (2)
GO Function (1)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
CYP1B1
CP1B, P4501b1
cytochrome P450, family 1, subfamily b, polypeptide 1
GO Process (40)
GO Function (4)
GO Component (3)
Gene Ontology Biological Process
- DNA modification [ISO]
- angiogenesis [IMP]
- arachidonic acid metabolic process [IDA, ISO]
- benzene-containing compound metabolic process [ISO]
- blood vessel morphogenesis [IMP]
- cell adhesion [IMP]
- cellular aromatic compound metabolic process [IDA, IMP, ISO]
- cellular response to hydrogen peroxide [IMP]
- cellular response to organic cyclic compound [ISO]
- collagen fibril organization [IMP]
- dibenzo-p-dioxin metabolic process [IMP]
- endothelial cell migration [IMP]
- endothelial cell-cell adhesion [IMP]
- estrogen metabolic process [IDA, ISO]
- intrinsic apoptotic signaling pathway in response to oxidative stress [IMP]
- membrane lipid catabolic process [IMP]
- negative regulation of NF-kappaB transcription factor activity [IMP]
- negative regulation of cell adhesion mediated by integrin [IMP]
- negative regulation of cell migration [IMP]
- negative regulation of cell proliferation [IMP]
- nitric oxide biosynthetic process [IMP]
- oxidation-reduction process [IDA]
- positive regulation of DNA biosynthetic process [ISO]
- positive regulation of JAK-STAT cascade [IMP]
- positive regulation of angiogenesis [IMP]
- positive regulation of apoptotic process [IMP]
- positive regulation of reactive oxygen species metabolic process [ISO]
- positive regulation of smooth muscle cell migration [ISO]
- positive regulation of translation [ISO]
- positive regulation vascular endothelial growth factor production [IMP]
- regulation of reactive oxygen species metabolic process [IMP]
- response to toxic substance [IMP]
- retina vasculature development in camera-type eye [IMP]
- retinal blood vessel morphogenesis [IMP]
- retinal metabolic process [IDA, ISO]
- retinol metabolic process [IDA, ISO]
- steroid metabolic process [ISO]
- toxin metabolic process [IMP]
- trabecular meshwork development [IMP]
- xenobiotic metabolic process [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Irisin Mediates Effects on Bone and Fat via ?V Integrin Receptors.
Irisin is secreted by muscle, increases with exercise, and mediates certain favorable effects of physical activity. In particular, irisin has been shown to have beneficial effects in adipose tissues, brain, and bone. However, the skeletal response to exercise is less clear, and the receptor for irisin has not been identified. Here we show that irisin binds to proteins of the ... [more]
Cell Dec. 13, 2017; 175(7);1756-1768.e17 [Pubmed: 30550785]
Throughput
- High Throughput
Curated By
- BioGRID