BAIT
CFD
Adn, DF
complement factor D (adipsin)
GO Process (2)
GO Function (1)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
TAOK1
2810468K05Rik, AU020252, D130018F14Rik, Map3k16, Markk, Psk2, mKIAA1361, RP23-273P3.2
TAO kinase 1
GO Process (12)
GO Function (4)
GO Component (2)
Gene Ontology Biological Process
- G2 DNA damage checkpoint [ISO]
- MAPK cascade [IBA]
- activation of MAPKK activity [IBA]
- cellular response to DNA damage stimulus [ISO]
- execution phase of apoptosis [ISO]
- intracellular signal transduction [IBA]
- positive regulation of JNK cascade [ISO]
- positive regulation of protein kinase activity [ISO]
- positive regulation of stress-activated MAPK cascade [ISO]
- protein phosphorylation [IBA, ISO]
- regulation of cytoskeleton organization [ISO]
- response to stress [IBA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Irisin Mediates Effects on Bone and Fat via ?V Integrin Receptors.
Irisin is secreted by muscle, increases with exercise, and mediates certain favorable effects of physical activity. In particular, irisin has been shown to have beneficial effects in adipose tissues, brain, and bone. However, the skeletal response to exercise is less clear, and the receptor for irisin has not been identified. Here we show that irisin binds to proteins of the ... [more]
Cell Dec. 13, 2017; 175(7);1756-1768.e17 [Pubmed: 30550785]
Throughput
- High Throughput
Curated By
- BioGRID