BAIT
CFD
Adn, DF
complement factor D (adipsin)
GO Process (2)
GO Function (1)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
RAP1A
AI848598, G-22K, Krev-1, Rap1
RAS-related protein-1a
GO Process (15)
GO Function (6)
GO Component (10)
Gene Ontology Biological Process
- GTP catabolic process [IDA]
- Rap protein signal transduction [ISO]
- cellular response to cAMP [ISO]
- cellular response to nerve growth factor stimulus [ISO]
- establishment of endothelial barrier [ISO]
- negative regulation of synaptic vesicle exocytosis [IGI]
- nerve growth factor signaling pathway [ISO]
- positive regulation of ERK1 and ERK2 cascade [IGI, ISO]
- positive regulation of Rap GTPase activity [ISO]
- positive regulation of neuron projection development [IDA, ISO]
- positive regulation of protein kinase activity [ISO]
- positive regulation of vasculogenesis [IMP]
- protein transport [ISO]
- regulation of cell junction assembly [ISO]
- small GTPase mediated signal transduction [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Irisin Mediates Effects on Bone and Fat via ?V Integrin Receptors.
Irisin is secreted by muscle, increases with exercise, and mediates certain favorable effects of physical activity. In particular, irisin has been shown to have beneficial effects in adipose tissues, brain, and bone. However, the skeletal response to exercise is less clear, and the receptor for irisin has not been identified. Here we show that irisin binds to proteins of the ... [more]
Cell Dec. 13, 2017; 175(7);1756-1768.e17 [Pubmed: 30550785]
Throughput
- High Throughput
Curated By
- BioGRID