BAIT
FNDC5
1500001L03Rik, AI836596, C87088, PeP, Pxp, RP23-284L6.4
fibronectin type III domain containing 5
GO Process (2)
GO Function (1)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
ANXA2
AW215814, Cal1h, CT009708.1
annexin A2
GO Process (15)
GO Function (8)
GO Component (26)
Gene Ontology Biological Process
- angiogenesis [IMP]
- body fluid secretion [ISO]
- cellular response to acid chemical [IDA]
- collagen fibril organization [IMP]
- fibrinolysis [IMP]
- membrane budding [ISO]
- membrane raft assembly [ISO]
- negative regulation of catalytic activity [ISO]
- osteoclast development [ISO]
- positive regulation of binding [IMP]
- positive regulation of fibroblast proliferation [ISO]
- positive regulation of protein phosphorylation [ISO]
- positive regulation of vesicle fusion [ISO]
- protein heterotetramerization [ISO]
- protein targeting to plasma membrane [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- Schmidt-Lanterman incisure [IDA]
- cell cortex [ISO]
- cell junction [ISS]
- cell surface [ISO]
- cytoplasm [IDA, ISO]
- early endosome [IDA]
- endosome [ISO]
- extracellular space [ISO]
- extracellular vesicular exosome [ISO]
- extrinsic component of plasma membrane [IDA]
- late endosome membrane [ISO]
- lipid particle [ISO]
- lysosomal membrane [ISO]
- macropinosome [ISO]
- membrane [ISO, ISS]
- membrane raft [ISO]
- midbody [ISO]
- myelin sheath adaxonal region [IDA]
- nucleus [ISO]
- perinuclear region of cytoplasm [ISO]
- plasma membrane [ISO]
- protein complex [ISO]
- ruffle [ISO]
- sarcolemma [IDA]
- stress fiber [ISS]
- vesicle [ISO]
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Irisin Mediates Effects on Bone and Fat via ?V Integrin Receptors.
Irisin is secreted by muscle, increases with exercise, and mediates certain favorable effects of physical activity. In particular, irisin has been shown to have beneficial effects in adipose tissues, brain, and bone. However, the skeletal response to exercise is less clear, and the receptor for irisin has not been identified. Here we show that irisin binds to proteins of the ... [more]
Cell Dec. 13, 2017; 175(7);1756-1768.e17 [Pubmed: 30550785]
Throughput
- High Throughput
Curated By
- BioGRID