BAIT
CFD
Adn, DF
complement factor D (adipsin)
GO Process (2)
GO Function (1)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
PRDX5
AOEB166, AOPP, Pmp20, Prdx6, PrxV
peroxiredoxin 5
GO Process (11)
GO Function (8)
GO Component (11)
Gene Ontology Biological Process
- NADPH oxidation [ISO]
- cellular response to reactive oxygen species [ISO]
- hydrogen peroxide catabolic process [ISO, ISS]
- negative regulation of apoptotic process [ISO]
- negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [ISO]
- negative regulation of oxidoreductase activity [ISO]
- negative regulation of transcription from RNA polymerase III promoter [ISO]
- positive regulation of collagen biosynthetic process [ISO]
- reactive nitrogen species metabolic process [ISO]
- regulation of apoptosis involved in tissue homeostasis [ISO]
- response to oxidative stress [ISO, ISS]
Gene Ontology Molecular Function- RNA polymerase III regulatory region DNA binding [ISO]
- antioxidant activity [ISO, ISS]
- cysteine-type endopeptidase inhibitor activity involved in apoptotic process [ISO]
- peroxidase activity [ISO]
- peroxiredoxin activity [ISO]
- peroxynitrite reductase activity [ISO]
- protein dimerization activity [ISO]
- receptor binding [ISO, ISS]
- RNA polymerase III regulatory region DNA binding [ISO]
- antioxidant activity [ISO, ISS]
- cysteine-type endopeptidase inhibitor activity involved in apoptotic process [ISO]
- peroxidase activity [ISO]
- peroxiredoxin activity [ISO]
- peroxynitrite reductase activity [ISO]
- protein dimerization activity [ISO]
- receptor binding [ISO, ISS]
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Irisin Mediates Effects on Bone and Fat via ?V Integrin Receptors.
Irisin is secreted by muscle, increases with exercise, and mediates certain favorable effects of physical activity. In particular, irisin has been shown to have beneficial effects in adipose tissues, brain, and bone. However, the skeletal response to exercise is less clear, and the receptor for irisin has not been identified. Here we show that irisin binds to proteins of the ... [more]
Cell Dec. 13, 2017; 175(7);1756-1768.e17 [Pubmed: 30550785]
Throughput
- High Throughput
Curated By
- BioGRID