BAIT
CFD
Adn, DF
complement factor D (adipsin)
GO Process (2)
GO Function (1)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
SOD2
MnSOD, Sod-2
superoxide dismutase 2, mitochondrial
GO Process (51)
GO Function (6)
GO Component (7)
Gene Ontology Biological Process
- age-dependent response to oxidative stress [IMP]
- age-dependent response to reactive oxygen species [ISO]
- apoptotic mitochondrial changes [IMP]
- detection of oxygen [IMP]
- erythrophore differentiation [IMP]
- glutathione metabolic process [IMP]
- heart development [IMP]
- hemopoiesis [IMP]
- hydrogen peroxide biosynthetic process [ISO]
- hydrogen peroxide metabolic process [ISO]
- intrinsic apoptotic signaling pathway in response to DNA damage [IMP]
- intrinsic apoptotic signaling pathway in response to oxidative stress [IMP]
- iron ion homeostasis [IMP]
- liver development [IMP]
- locomotory behavior [IMP]
- mitochondrion organization [IMP]
- negative regulation of apoptotic process [ISO]
- negative regulation of cell proliferation [ISO]
- negative regulation of fat cell differentiation [IMP]
- negative regulation of fibroblast proliferation [IDA]
- negative regulation of neuron apoptotic process [ISO]
- negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [ISO]
- neuron development [IMP]
- oxidation-reduction process [ISO]
- oxygen homeostasis [ISO]
- positive regulation of nitric oxide biosynthetic process [IMP]
- post-embryonic development [IMP]
- protein homooligomerization [ISO]
- protein homotetramerization [ISO]
- regulation of blood pressure [IMP]
- regulation of catalytic activity [IMP]
- regulation of mitochondrial membrane potential [IMP]
- regulation of transcription from RNA polymerase II promoter [IDA, ISO]
- release of cytochrome c from mitochondria [IMP]
- removal of superoxide radicals [IDA, IMP, ISO]
- respiratory electron transport chain [IMP]
- response to activity [IMP]
- response to axon injury [IMP]
- response to drug [ISO]
- response to gamma radiation [IGI]
- response to hydrogen peroxide [IMP]
- response to hyperoxia [IMP]
- response to nutrient levels [ISO]
- response to oxidative stress [IGI, IMP]
- response to reactive oxygen species [IMP]
- response to superoxide [IMP, ISO]
- sensory perception of sound [IMP]
- superoxide anion generation [IMP]
- superoxide metabolic process [IMP, ISO]
- vasodilation [IMP]
- vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Irisin Mediates Effects on Bone and Fat via ?V Integrin Receptors.
Irisin is secreted by muscle, increases with exercise, and mediates certain favorable effects of physical activity. In particular, irisin has been shown to have beneficial effects in adipose tissues, brain, and bone. However, the skeletal response to exercise is less clear, and the receptor for irisin has not been identified. Here we show that irisin binds to proteins of the ... [more]
Cell Dec. 13, 2017; 175(7);1756-1768.e17 [Pubmed: 30550785]
Throughput
- High Throughput
Curated By
- BioGRID