BAIT
FNDC5
1500001L03Rik, AI836596, C87088, PeP, Pxp, RP23-284L6.4
fibronectin type III domain containing 5
GO Process (2)
GO Function (1)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
PHB
Bap32, RP23-17C2.2
prohibitin
GO Process (16)
GO Function (4)
GO Component (11)
Gene Ontology Biological Process
- DNA biosynthetic process [IMP]
- cellular response to interleukin-6 [ISO]
- histone deacetylation [ISO]
- negative regulation of androgen receptor signaling pathway [ISO]
- negative regulation of apoptotic process [ISO]
- negative regulation of cell growth [ISO]
- negative regulation of cell proliferation [ISO]
- negative regulation of glucocorticoid receptor signaling pathway [ISO]
- negative regulation of transcription by competitive promoter binding [ISO]
- negative regulation of transcription from RNA polymerase II promoter [IDA, ISO]
- negative regulation of transcription, DNA-templated [ISO]
- osteoblast differentiation [ISO]
- positive regulation of transcription, DNA-templated [ISO]
- progesterone receptor signaling pathway [ISO]
- regulation of transcription, DNA-templated [ISO]
- transcription from RNA polymerase II promoter [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- cytoplasm [ISO]
- extracellular vesicular exosome [ISO]
- extrinsic component of mitochondrial outer membrane [ISO]
- integral component of plasma membrane [ISO]
- membrane [ISO]
- mitochondrial crista [ISO]
- mitochondrial inner membrane [IDA]
- mitochondrion [IDA, ISO]
- myelin sheath [IDA]
- nucleoplasm [ISO]
- nucleus [IDA, ISO]
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Irisin Mediates Effects on Bone and Fat via ?V Integrin Receptors.
Irisin is secreted by muscle, increases with exercise, and mediates certain favorable effects of physical activity. In particular, irisin has been shown to have beneficial effects in adipose tissues, brain, and bone. However, the skeletal response to exercise is less clear, and the receptor for irisin has not been identified. Here we show that irisin binds to proteins of the ... [more]
Cell Dec. 13, 2017; 175(7);1756-1768.e17 [Pubmed: 30550785]
Throughput
- High Throughput
Curated By
- BioGRID