BAIT
FNDC5
1500001L03Rik, AI836596, C87088, PeP, Pxp, RP23-284L6.4
fibronectin type III domain containing 5
GO Process (2)
GO Function (1)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
PDK3
2610001M10Rik, AI035637, RP23-369L6.2
pyruvate dehydrogenase kinase, isoenzyme 3
GO Process (8)
GO Function (4)
GO Component (2)
Gene Ontology Biological Process
- cellular response to fatty acid [ISO]
- cellular response to glucose stimulus [ISO]
- hypoxia-inducible factor-1alpha signaling pathway [ISO]
- peptidyl-serine phosphorylation [ISO]
- peroxisome proliferator activated receptor signaling pathway [ISO]
- regulation of acetyl-CoA biosynthetic process from pyruvate [ISO]
- regulation of glucose metabolic process [ISO]
- regulation of reactive oxygen species metabolic process [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- cell [ISO]
- mitochondrion [IDA]
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Irisin Mediates Effects on Bone and Fat via ?V Integrin Receptors.
Irisin is secreted by muscle, increases with exercise, and mediates certain favorable effects of physical activity. In particular, irisin has been shown to have beneficial effects in adipose tissues, brain, and bone. However, the skeletal response to exercise is less clear, and the receptor for irisin has not been identified. Here we show that irisin binds to proteins of the ... [more]
Cell Dec. 13, 2017; 175(7);1756-1768.e17 [Pubmed: 30550785]
Throughput
- High Throughput
Curated By
- BioGRID