BAIT
FNDC5
1500001L03Rik, AI836596, C87088, PeP, Pxp, RP23-284L6.4
fibronectin type III domain containing 5
GO Process (2)
GO Function (1)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
MAGI2
AIP-1, Acvri1, Acvrinp1, Acvrip1, Magi-2, S-SCAM, mKIAA0705
membrane associated guanylate kinase, WW and PDZ domain containing 2
GO Process (15)
GO Function (9)
GO Component (11)
Gene Ontology Biological Process
- SMAD protein signal transduction [IDA]
- cellular response to nerve growth factor stimulus [ISO]
- cytoplasmic transport [ISO]
- mitotic cell cycle arrest [ISO]
- negative regulation of activin receptor signaling pathway [IDA]
- negative regulation of cell migration [ISO]
- negative regulation of cell proliferation [ISO]
- negative regulation of protein kinase B signaling [ISO]
- nerve growth factor signaling pathway [ISO]
- positive regulation of neuron projection development [ISO]
- positive regulation of phosphoprotein phosphatase activity [ISO]
- positive regulation of receptor internalization [ISO]
- protein heterooligomerization [ISO]
- receptor clustering [ISO]
- signal transduction [IPI]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Irisin Mediates Effects on Bone and Fat via ?V Integrin Receptors.
Irisin is secreted by muscle, increases with exercise, and mediates certain favorable effects of physical activity. In particular, irisin has been shown to have beneficial effects in adipose tissues, brain, and bone. However, the skeletal response to exercise is less clear, and the receptor for irisin has not been identified. Here we show that irisin binds to proteins of the ... [more]
Cell Dec. 13, 2017; 175(7);1756-1768.e17 [Pubmed: 30550785]
Throughput
- High Throughput
Curated By
- BioGRID