BAIT
TNC
150-225, DFNA56, GMEM, GP, HXB, JI, TN, TN-C
tenascin C
GO Process (3)
GO Function (1)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
SPARC
ON
secreted protein, acidic, cysteine-rich (osteonectin)
GO Process (8)
GO Function (3)
GO Component (10)
Gene Ontology Biological Process
- blood coagulation [TAS]
- extracellular matrix organization [TAS]
- negative regulation of angiogenesis [IDA]
- negative regulation of endothelial cell proliferation [IDA]
- platelet activation [TAS]
- platelet degranulation [TAS]
- positive regulation of endothelial cell migration [IDA]
- regulation of cell morphogenesis [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
SMOC1 is a tenascin-C interacting protein over-expressed in brain tumors.
Tenascin-C is an extracellular matrix protein over-expressed in a large variety of cancers. In the present study, we aimed at identifying new interactors of tenascin-C by purifying secreted proteins on a tenascin-C affinity column. Analysis of eluates by mass spectrometry revealed phosphoglycerate kinase 1, clusterin, fibronectin, SPARC-related modular calcium-binding protein 1 (SMOC1) and nidogen-2 as potential interactors of tenascin-C. The ... [more]
Matrix Biol Apr. 01, 2011; 30(3);225-33 [Pubmed: 21349332]
Throughput
- Low Throughput
Curated By
- BioGRID