MYH10
Gene Ontology Biological Process
- ATP catabolic process [ISO]
- actin cytoskeleton organization [ISO]
- actin filament-based movement [ISO]
- actomyosin structure organization [ISO]
- adult heart development [ISO]
- axon guidance [ISO]
- axonogenesis [ISO]
- brain development [ISO]
- cardiac myofibril assembly [ISO]
- cell proliferation [ISO]
- cellular component movement [NAS]
- cerebellar Purkinje cell layer development [ISO]
- exocytosis [ISO]
- fourth ventricle development [ISO]
- in utero embryonic development [ISO]
- lateral ventricle development [ISO]
- mitotic cytokinesis [ISO]
- myofibril assembly [ISO]
- neuromuscular process controlling balance [ISO]
- neuron migration [ISO]
- neuron projection development [ISO]
- nuclear migration [ISO]
- plasma membrane repair [ISO]
- regulation of cell shape [ISO]
- retina development in camera-type eye [ISO]
- substrate-dependent cell migration, cell extension [ISO]
- third ventricle development [ISO]
- ventricular cardiac muscle cell development [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- actin cytoskeleton [ISO]
- actomyosin [ISO]
- axon [ISO]
- cell cortex [ISO]
- cleavage furrow [ISO]
- cytoplasm [ISO]
- dendritic spine [ISO]
- extracellular vesicular exosome [ISO]
- growth cone [ISO]
- midbody [ISO]
- mitochondrion [ISO]
- myosin II complex [ISO]
- myosin II filament [ISO]
- myosin complex [ISO]
- neuromuscular junction [ISO]
- neuron projection [ISO]
- neuronal cell body [ISO]
- nucleus [ISO]
- plasma membrane [ISO]
- spindle [ISO]
- stress fiber [ISO]
SCN2A
Gene Ontology Biological Process
- intrinsic apoptotic signaling pathway in response to osmotic stress [ISO]
- membrane depolarization during action potential [IBA]
- myelination [IEP]
- nervous system development [ISO]
- neuron apoptotic process [ISO]
- neuronal action potential [IBA, IDA, TAS]
- sodium ion transmembrane transport [IBA, IDA, ISO]
- sodium ion transport [IDA, ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- T-tubule [ISO]
- axon [ISO]
- axon initial segment [IDA]
- intercalated disc [ISO]
- intracellular [ISO]
- intrinsic component of plasma membrane [IDA]
- membrane [ISO]
- neuron projection [IDA]
- node of Ranvier [IDA]
- paranode region of axon [ISO]
- plasma membrane [IBA]
- sodium channel complex [IDA]
- voltage-gated sodium channel complex [IDA]
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Nonmuscle myosin II isoforms interact with sodium channel alpha subunits.
Sodium channels play pivotal roles in health and diseases due to their ability to control cellular excitability. The pore-forming ?-subunits (sodium channel alpha subunits) of the voltage-sensitive channels (i.e., Nav1.1-1.9) and the nonvoltage-dependent channel (i.e., Nax) share a common structural motif and selectivity for sodium ions. We hypothesized that the actin-based nonmuscle myosin II motor proteins, nonmuscle myosin heavy chain-IIA/myh9, ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID