UHMK1
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
KIF3A
Gene Ontology Biological Process
- ATP catabolic process [IBA]
- anterior/posterior pattern specification [IMP]
- cilium assembly [IMP]
- cilium morphogenesis [IMP]
- determination of left/right symmetry [IMP]
- dorsal/ventral neural tube patterning [IGI, IMP]
- dorsal/ventral pattern formation [IMP]
- epidermal stem cell homeostasis [IMP]
- epidermis development [IMP]
- heart development [IMP]
- in utero embryonic development [IGI]
- inner ear receptor stereocilium organization [IMP]
- kidney development [IMP]
- microtubule-based movement [IBA]
- positive regulation of epithelial cell proliferation [IMP]
- positive regulation of receptor-mediated endocytosis [ISO]
- smoothened signaling pathway [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- axoneme [ISO]
- centrosome [ISO]
- cilium [IDA]
- extracellular vesicular exosome [ISO]
- intraciliary transport particle [IDA]
- kinesin II complex [IDA, ISO]
- microtubule cytoskeleton [ISO]
- neuron projection [IDA]
- photoreceptor connecting cilium [IDA]
- primary cilium [IDA]
- spindle microtubule [ISO]
- synaptic vesicle [ISO]
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Protein kinase KIS localizes to RNA granules and enhances local translation.
The regulation of mRNA transport is a fundamental process for cytoplasmic sorting of transcripts and spatially controlled translational derepression once properly localized. There is growing evidence that translation is locally modulated as a result of specific synaptic inputs. However, the underlying molecular mechanisms that regulate this translational process are just emerging. We show that KIS, a serine/threonine kinase functionally related ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| UHMK1 KIF3A | Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation. | Low | - | BioGRID | - |
Curated By
- BioGRID