BAIT
ELAVL4
HUD, PNEM
ELAV like neuron-specific RNA binding protein 4
GO Process (2)
GO Function (3)
GO Component (0)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
PREY
IGF2BP1
Imp1, ZBP1
insulin-like growth factor 2 mRNA binding protein 1
GO Process (6)
GO Function (5)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
FRET
An interaction is inferred when close proximity of interaction partners is detected by fluorescence resonance energy transfer between pairs of fluorophore-labeled molecules, such as occurs between CFP (donor) and YFP (acceptor) fusion proteins.
Publication
Dynamics of survival of motor neuron (SMN) protein interaction with the mRNA-binding protein IMP1 facilitates its trafficking into motor neuron axons.
Spinal muscular atrophy (SMA) is a lethal neurodegenerative disease specifically affecting spinal motor neurons. SMA is caused by the homozygous deletion or mutation of the survival of motor neuron 1 (SMN1) gene. The SMN protein plays an essential role in the assembly of spliceosomal ribonucleoproteins. However, it is still unclear how low levels of the ubiquitously expressed SMN protein lead ... [more]
Dev Neurobiol Mar. 01, 2014; 74(3);319-332 [Pubmed: 23897586]
Throughput
- Low Throughput
Additional Notes
- Bimolecular Fluorescence Complementation. Species of bait is unclear
Curated By
- BioGRID