Protein-RNA

An interaction is detected between and protein and an RNA in vitro.

Publication

Demonstration and characterization of the iron regulatory protein in human brain.

Hu J, Connor JR

Iron regulatory proteins (IRPs) are cytoplasmic RNA binding proteins that regulate expression of ferritin, erythroid 5-aminolevulinic acid synthase, and transferrin receptor through interaction with conserved RNA stem-loop structures called iron-responsive elements (IREs). Two IRPs (IRP1 and IRP2) have been reported. In the present study we provide evidence for and initial characterization of the IRPs in human brain. Two RNA-protein complexes ... [more]

J Neurochem Aug. 01, 1996; 67(2);838-44 [Pubmed: 8764614]

Throughput

  • Low Throughput

Curated By

  • BioGRID