BAIT

AGO2

EIF2C2, Q10

argonaute RISC catalytic component 2

GO Process (18)

GO Function (7)

GO Component (9)

Gene Ontology Biological Process

Fc-epsilon receptor signaling pathway [TAS]

Notch signaling pathway [TAS]

RNA phosphodiester bond hydrolysis, endonucleolytic [EXP, IDA]

epidermal growth factor receptor signaling pathway [TAS]

fibroblast growth factor receptor signaling pathway [TAS]

gene expression [TAS]

gene silencing by RNA [ISS]

innate immune response [TAS]

mRNA cleavage involved in gene silencing by miRNA [IDA, IMP]

negative regulation of translation involved in gene silencing by miRNA [IDA, IMP]

negative regulation of translational initiation [IDA]

neurotrophin TRK receptor signaling pathway [TAS]

phosphatidylinositol-mediated signaling [TAS]

positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [ISS]

positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [ISS]

pre-miRNA processing [IDA]

translation [NAS]

translational initiation [NAS]

Gene Ontology Molecular Function

RNA 7-methylguanosine cap binding [IDA]
endoribonuclease activity [EXP]
endoribonuclease activity, cleaving siRNA-paired mRNA [IDA]
poly(A) RNA binding [IDA]
protein binding [IPI]
siRNA binding [IDA]
translation initiation factor activity [NAS]

Gene Ontology Cellular Component

RISC complex [IDA]

cytoplasm [IDA]

cytoplasmic mRNA processing body [IDA]

mRNA cap binding complex [IDA]

micro-ribonucleoprotein complex [IDA]

ribonucleoprotein complex [IDA]

CRISPR Database OMIM HGNC Alliance of Genome Resources Entrez Gene RefSeq UniprotKB Ensembl

Homo sapiens

PREY

SHPRH

bA545I5.2, RP11-545I5.1

SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase

Fanconi Anemia Project

GO Process (1)

GO Function (1)

GO Component (0)

Gene Ontology Biological Process

protein polyubiquitination [IDA]

Gene Ontology Molecular Function

ubiquitin-protein transferase activity [IDA]

CRISPR Database HGNC Alliance of Genome Resources OMIM Entrez Gene RefSeq UniprotKB Ensembl

Homo sapiens

Affinity Capture-RNA

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and associated RNA species identified by Northern blot, RT-PCR, affinity labeling, sequencing, or microarray analysis.

Publication

Circular RNA hsa_circ_0001649 inhibits hepatocellular carcinoma progression via multiple miRNAs sponge.

Su Y, Xu C, Liu Y, Hu Y, Wu H

Circular RNA (circRNA) exerts an essential role in tumor development. Hsa_circ_0001649 (circ-0001649) was produced at the SHPRH gene locus containing exon 26-29. This study analyzed the specific mechanism of circ-0001649 in influencing the development of hepatocellular carcinoma (HCC). Relative levels of circ-0001649 in HCC cell lines and tissues were examined by qRT-PCR. The direct binding between circ-0001649 and miR-127-5p/miR-612/miR-4688 were ... [more]

Aging (Albany NY) Dec. 28, 2018; 11(10);3362-3375 [Pubmed: 31137016]

Throughput

Low Throughput

Additional Notes

circ-0001649 RNA from the SHPRH gene

Curated By

BioGRID