BAIT
PRRG4
PRGP4, TMG4
proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
GO Process (0)
GO Function (0)
GO Component (1)
Gene Ontology Cellular Component
Homo sapiens
PREY
VAV2
VAV-2
vav 2 guanine nucleotide exchange factor
GO Process (15)
GO Function (2)
GO Component (1)
Gene Ontology Biological Process
- Fc-epsilon receptor signaling pathway [TAS]
- Fc-gamma receptor signaling pathway involved in phagocytosis [TAS]
- apoptotic signaling pathway [TAS]
- axon guidance [TAS]
- blood coagulation [TAS]
- innate immune response [TAS]
- neurotrophin TRK receptor signaling pathway [TAS]
- platelet activation [TAS]
- positive regulation of GTPase activity [EXP, TAS]
- positive regulation of apoptotic process [TAS]
- regulation of blood coagulation [IMP]
- regulation of gene expression [IMP]
- regulation of small GTPase mediated signal transduction [TAS]
- signal transduction [TAS]
- small GTPase mediated signal transduction [TAS]
Gene Ontology Molecular Function
Homo sapiens
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
Cellular localization and characterization of cytosolic binding partners for Gla domain-containing proteins PRRG4 and PRRG2.
The genes encoding a family of proteins termed proline-rich ?-carboxyglutamic acid (PRRG) proteins were identified and characterized more than a decade ago, but their functions remain unknown. These novel membrane proteins have an extracellular ?-carboxyglutamic acid (Gla) protein domain and cytosolic WW binding motifs. We screened WW domain arrays for cytosolic binding partners for PRRG4 and identified novel protein-protein interactions ... [more]
J Biol Chem Sep. 06, 2013; 288(36);25908-25914 [Pubmed: 23873930]
Throughput
- High Throughput
Curated By
- BioGRID