BAIT
EZH2
ENX-1, ENX1, EZH1, EZH2b, KMT6, KMT6A, WVS, WVS2
enhancer of zeste 2 polycomb repressive complex 2 subunit
GO Process (12)
GO Function (7)
GO Component (4)
Gene Ontology Biological Process
- chromatin organization [TAS]
- histone H3-K27 methylation [IDA]
- negative regulation of gene expression, epigenetic [IDA]
- negative regulation of retinoic acid receptor signaling pathway [IMP]
- negative regulation of transcription from RNA polymerase II promoter [IDA]
- negative regulation of transcription, DNA-templated [IMP]
- positive regulation of MAP kinase activity [IDA]
- positive regulation of Ras GTPase activity [IDA]
- positive regulation of epithelial to mesenchymal transition [IDA]
- positive regulation of protein serine/threonine kinase activity [IDA]
- regulation of circadian rhythm [IMP]
- regulation of transcription, DNA-templated [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
LINC00511
long intergenic non-protein coding RNA 511
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
Protein-RNA
An interaction is detected between and protein and an RNA in vitro.
Publication
LINC00511 promotes the progression of non-small cell lung cancer through downregulating LATS2 and KLF2 by binding to EZH2 and LSD1.
Lung cancer is a malignant tumor with extremely high morbidity and mortality. Recent studies have identified the vital role of LINC00511 (lncRNAs) in the development and progression of non-small cell lung cancer (NSCLC). In this research, we aim to explore the biological function of LINC00511 in the development and metastasis of NSCLC.LINC00511 expression in 57 paired NSCLC patients' tissues and ... [more]
Eur Rev Med Pharmacol Sci Oct. 01, 2019; 23(19);8377-8390 [Pubmed: 31646568]
Throughput
- Low Throughput
Curated By
- BioGRID