Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Publication

Structural and functional characterization of Kv6.2 a new gamma-subunit of voltage-gated potassium channel.

Zhu XR, Netzer R, Boehlke K, Liu Q, Pongs O

We have cloned and functionally expressed Kv6.2, a new member of the Kv6 subfamily of voltage-gated potassium channel subunits. The human Kv6.2 (KCNF2) gene was mapped at 18q22-18q23. Kv6.2 mRNA is preferentially expressed in rat and human myocard. Rat and human Kv6.2 subunits appear to be unable to form functional Kv channels in a heterologous expression system, but, when coexpressed ... [more]

Recept. Channels Nov. 07, 1999; 6(5);337-50 [Pubmed: 10551266]

Throughput

  • Low Throughput

Curated By

  • BioGRID