BAIT
ZBED1
ALTE, DREF, TRAMP, hDREF
zinc finger, BED-type containing 1
GO Process (1)
GO Function (1)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
RANBP9
BPM-L, BPM90, RANBPM, RanBP7
RAN binding protein 9
GO Process (3)
GO Function (3)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Transcription Factor hDREF Is a Novel SUMO E3 Ligase of Mi2?.
The human transcription factor DNA replication-related element-binding factor (hDREF) is essential for the transcription of a number of housekeeping genes. The mechanisms underlying constitutively active transcription by hDREF were unclear. Here, we provide evidence that hDREF possesses small ubiquitin-like modifier (SUMO) ligase activity and can specifically SUMOylate Mi2?, an ATP-dependent DNA helicase in the nucleosome remodeling and deacetylation complex. Moreover, ... [more]
J Biol Chem May. 27, 2016; 291(22);11619-34 [Pubmed: 27068747]
Throughput
- High Throughput
Curated By
- BioGRID