SLC1A2
Gene Ontology Biological Process
- D-aspartate import [ISO]
- L-glutamate import [ISO]
- L-glutamate transmembrane transport [IMP, ISO]
- L-glutamate transport [IDA, IMP, ISO]
- adult behavior [IMP]
- cellular response to extracellular stimulus [IMP]
- multicellular organism growth [IMP]
- multicellular organismal aging [IMP]
- nervous system development [IMP]
- positive regulation of glucose import [IMP]
- response to amino acid [IMP]
- response to drug [IMP]
- response to light stimulus [IMP]
- response to wounding [IMP]
- sodium ion transmembrane transport [ISO]
- telencephalon development [IMP]
- visual behavior [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
SLC1A2
Gene Ontology Biological Process
- D-aspartate import [ISO]
- L-glutamate import [ISO]
- L-glutamate transmembrane transport [IMP, ISO]
- L-glutamate transport [IDA, IMP, ISO]
- adult behavior [IMP]
- cellular response to extracellular stimulus [IMP]
- multicellular organism growth [IMP]
- multicellular organismal aging [IMP]
- nervous system development [IMP]
- positive regulation of glucose import [IMP]
- response to amino acid [IMP]
- response to drug [IMP]
- response to light stimulus [IMP]
- response to wounding [IMP]
- sodium ion transmembrane transport [ISO]
- telencephalon development [IMP]
- visual behavior [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
The four major N- and C-terminal splice variants of the excitatory amino acid transporter GLT-1 form cell surface homomeric and heteromeric assemblies.
The L-glutamate transporter GLT-1 is an abundant central nervous system (CNS) membrane protein of the excitatory amino acid transporter (EAAT) family that controls extracellular L-glutamate levels and is important in limiting excitotoxic neuronal death. Using reverse transcription-polymerase chain reaction, we have determined that four mRNAs encoding GLT-1 exist in mouse brain, with the potential to encode four GLT-1 isoforms that ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| SLC1A2 SLC1A2 | FRET FRET An interaction is inferred when close proximity of interaction partners is detected by fluorescence resonance energy transfer between pairs of fluorophore-labeled molecules, such as occurs between CFP (donor) and YFP (acceptor) fusion proteins. | Low | - | BioGRID | - |
Curated By
- BioGRID