BAIT
FMR1
FMRP, FRAXA, POF, POF1
fragile X mental retardation 1
GO Process (2)
GO Function (4)
GO Component (7)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
MAGED1
DLXIN-1, NRAGE, PRO2292
melanoma antigen family D, 1
GO Process (8)
GO Function (1)
GO Component (3)
Gene Ontology Biological Process
- apoptotic process [TAS]
- apoptotic signaling pathway [TAS]
- circadian regulation of gene expression [ISS]
- negative regulation of epithelial cell proliferation [IDA]
- neurotrophin TRK receptor signaling pathway [TAS]
- positive regulation of apoptotic process [TAS]
- regulation of apoptotic process [TAS]
- regulation of transcription, DNA-templated [TAS]
Gene Ontology Molecular Function
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Identification of Human Neuronal Protein Complexes Reveals Biochemical Activities and Convergent Mechanisms of Action in Autism Spectrum Disorders.
The prevalence of autism spectrum disorders (ASDs) is rapidly growing, yet its molecular basis is poorly understood. We used a systems approach in which ASD candidate genes were mapped onto the ubiquitous human protein complexes and the resulting complexes were characterized. The studies revealed the role of histone deacetylases (HDAC1/2) in regulating the expression of ASD orthologs in the embryonic ... [more]
Cell Syst Nov. 25, 2015; 1(5);361-374 [Pubmed: 26949739]
Throughput
- High Throughput
Additional Notes
- SAINT probability >80%
Curated By
- BioGRID