BAIT
GRB7
growth factor receptor bound protein 7
GO Process (3)
GO Function (3)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
PABPC1
Pabp, Pabp1
poly(A) binding protein, cytoplasmic 1
GO Process (4)
GO Function (6)
GO Component (9)
Gene Ontology Biological Process
- gene silencing by RNA [ISO, ISS]
- negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [ISO, ISS]
- positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [ISO, ISS]
- positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [ISO, ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Partners of wild type Grb7 and a mutant lacking its calmodulin-binding domain.
Growth factor receptor bound protein 7 (Grb7) is a mammalian adaptor protein participating in signaling pathways implicated in cell migration, metastatic invasion, cell proliferation and tumor-associated angiogenesis. We expressed tagged versions of wild type Grb7 and the mutant Grb7?, lacking its calmodulin-binding domain (CaM-BD), in human embryonic kidney (HEK) 293 cells and rat glioma C6 cells to identify novel binding partners ... [more]
Arch Biochem Biophys Dec. 15, 2019; 687();108386 [Pubmed: 32360748]
Throughput
- High Throughput
Curated By
- BioGRID