BAIT
AGO2
EIF2C2, Q10
argonaute RISC catalytic component 2
GO Process (18)
GO Function (7)
GO Component (9)
Gene Ontology Biological Process
- Fc-epsilon receptor signaling pathway [TAS]
- Notch signaling pathway [TAS]
- RNA phosphodiester bond hydrolysis, endonucleolytic [EXP, IDA]
- epidermal growth factor receptor signaling pathway [TAS]
- fibroblast growth factor receptor signaling pathway [TAS]
- gene expression [TAS]
- gene silencing by RNA [ISS]
- innate immune response [TAS]
- mRNA cleavage involved in gene silencing by miRNA [IDA, IMP]
- negative regulation of translation involved in gene silencing by miRNA [IDA, IMP]
- negative regulation of translational initiation [IDA]
- neurotrophin TRK receptor signaling pathway [TAS]
- phosphatidylinositol-mediated signaling [TAS]
- positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [ISS]
- positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [ISS]
- pre-miRNA processing [IDA]
- translation [NAS]
- translational initiation [NAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
SOCS5
CIS6, CISH6, Cish5, SOCS-5
suppressor of cytokine signaling 5
GO Process (8)
GO Function (3)
GO Component (1)
Gene Ontology Biological Process
- cell growth [NAS]
- cytokine-mediated signaling pathway [IBA, ISS]
- negative regulation of JAK-STAT cascade [IBA]
- negative regulation of T-helper 2 cell differentiation [ISS]
- negative regulation of epidermal growth factor-activated receptor activity [IDA]
- negative regulation of signal transduction [NAS]
- positive regulation of T-helper 1 cell differentiation [ISS]
- positive regulation of proteasomal ubiquitin-dependent protein catabolic process [IMP]
Gene Ontology Molecular Function
Homo sapiens
Affinity Capture-RNA
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and associated RNA species identified by Northern blot, RT-PCR, affinity labeling, sequencing, or microarray analysis.
Publication
lncRNA HAND2-AS1 Inhibits Liver Cancer Cell Proliferation and Migration by Upregulating SOCS5 to Inactivate the JAK-STAT Pathway.
Objective: lncRNA HAND2 antisense RNA 1 (HAND2-AS1) is consistently well recognized to suppress multiple tumors, while ... [more]
Cancer Biother Radiopharm Mar. 01, 2020; 35(2);143-152 [Pubmed: 32155348]
Throughput
- Low Throughput
Curated By
- BioGRID