BAIT

MSRA

PMSR
methionine sulfoxide reductase A
GO Process (2)
GO Function (0)
GO Component (4)
Homo sapiens
PREY

FARSB

FARSLB, FRSB, PheHB, PheRS, HSPC173
phenylalanyl-tRNA synthetase, beta subunit
GO Process (3)
GO Function (0)
GO Component (3)

Gene Ontology Cellular Component

Homo sapiens

Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Publication

The Antioxidant Enzyme Methionine Sulfoxide Reductase A (MsrA) Interacts with Jab1/CSN5 and Regulates Its Function.

Jiang B, Adams Z, Moonah S, Shi H, Maupin-Furlow J, Moskovitz J

Methionine sulfoxide (MetO) is an oxidative posttranslational modification that primarily occurs under oxidative stress conditions, leading to alteration of protein structure and function. This modification is regulated by MetO reduction through the evolutionarily conserved methionine sulfoxide reductase (Msr) system. The Msr type A enzyme (MsrA) plays an important role as a cellular antioxidant and promotes cell survival. The ubiquitin- (Ub) ... [more]

Antioxidants (Basel) May. 24, 2020; 9(5); [Pubmed: 32456285]

Throughput

  • High Throughput

Curated By

  • BioGRID