BAIT
SLIT2
SLIL3, Slit-2
slit homolog 2 (Drosophila)
GO Process (37)
GO Function (9)
GO Component (7)
Gene Ontology Biological Process
- Roundabout signaling pathway [IC, IMP]
- apoptotic process involved in luteolysis [IEP]
- axon extension involved in axon guidance [IDA]
- axon guidance [IDA, TAS]
- branching morphogenesis of an epithelial tube [IDA, IMP]
- cell migration involved in sprouting angiogenesis [IMP]
- cellular response to heparin [IDA]
- cellular response to hormone stimulus [IEP]
- chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration [IDA]
- chemorepulsion involved in postnatal olfactory bulb interneuron migration [IDA]
- corticospinal neuron axon guidance through spinal cord [IMP]
- induction of negative chemotaxis [IDA]
- motor neuron axon guidance [IDA]
- negative chemotaxis [IDA, IMP]
- negative regulation of actin filament polymerization [IDA]
- negative regulation of catalytic activity [IDA]
- negative regulation of cell growth [IMP]
- negative regulation of cell migration [IDA, IMP]
- negative regulation of cellular response to growth factor stimulus [IDA]
- negative regulation of chemokine-mediated signaling pathway [IMP]
- negative regulation of endothelial cell migration [IDA]
- negative regulation of lamellipodium assembly [IDA]
- negative regulation of leukocyte chemotaxis [IDA]
- negative regulation of monocyte chemotaxis [ISS]
- negative regulation of mononuclear cell migration [IDA]
- negative regulation of neutrophil chemotaxis [IDA]
- negative regulation of protein phosphorylation [IDA]
- negative regulation of retinal ganglion cell axon guidance [IDA]
- negative regulation of small GTPase mediated signal transduction [IDA]
- negative regulation of smooth muscle cell chemotaxis [IDA]
- negative regulation of smooth muscle cell migration [IDA]
- negative regulation of vascular permeability [IDA]
- positive regulation of apoptotic process [IMP]
- positive regulation of axonogenesis [TAS]
- response to cortisol [IEP]
- retinal ganglion cell axon guidance [IDA]
- ureteric bud development [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
RPS21
HLDF, S21, RP5-908M14.8
ribosomal protein S21
GO Process (16)
GO Function (3)
GO Component (4)
Gene Ontology Biological Process
- RNA metabolic process [TAS]
- SRP-dependent cotranslational protein targeting to membrane [TAS]
- cellular protein metabolic process [TAS]
- endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [IBA]
- endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [IBA]
- gene expression [TAS]
- mRNA metabolic process [TAS]
- nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [TAS]
- ribosomal small subunit biogenesis [IBA]
- translation [IC, NAS, TAS]
- translational elongation [TAS]
- translational initiation [TAS]
- translational termination [TAS]
- viral life cycle [TAS]
- viral process [TAS]
- viral transcription [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Human-chromatin-related protein interactions identify a demethylase complex required for chromosome segregation.
Chromatin regulation is driven by multicomponent protein complexes, which form functional modules. Deciphering the components of these modules and their interactions is central to understanding the molecular pathways these proteins are regulating, their functions, and their relation to both normal development and disease. We describe the use of affinity purifications of tagged human proteins coupled with mass spectrometry to generate ... [more]
Cell Rep Jul. 10, 2014; 8(1);297-310 [Pubmed: 24981860]
Quantitative Score
- 13.71208919 [HGSCore]
Throughput
- High Throughput
Additional Notes
- Affinity Capture MS carried out to identify high confidence protein interactions with a iHGSCore < 11
Curated By
- BioGRID