BAIT
MKRN2
RNF62, HSPC070
makorin ring finger protein 2
GO Process (0)
GO Function (2)
GO Component (1)
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
ATP6V0D1
ATP6D, ATP6DV, P39, VATX, VMA6, VPATPD
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1
GO Process (11)
GO Function (1)
GO Component (7)
Gene Ontology Biological Process
- activation of signaling protein activity involved in unfolded protein response [TAS]
- cellular iron ion homeostasis [TAS]
- cellular protein metabolic process [TAS]
- cilium assembly [ISS]
- endoplasmic reticulum unfolded protein response [TAS]
- insulin receptor signaling pathway [TAS]
- interaction with host [TAS]
- phagosome maturation [TAS]
- proton transport [NAS]
- transferrin transport [TAS]
- transmembrane transport [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-RNA
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and associated RNA species identified by Northern blot, RT-PCR, affinity labeling, sequencing, or microarray analysis.
Publication
MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.
The mammalian mRNA nuclear export process is thought to terminate at the cytoplasmic face of the nuclear pore complex through ribonucleoprotein remodeling. We conduct a stringent affinity-purification mass-spectrometry-based screen of the physical interactions of human RNA-binding E3 ubiquitin ligases. The resulting protein-interaction network reveals interactions between the RNA-binding E3 ubiquitin ligase MKRN2 and GLE1, a DEAD-box helicase activator implicated in ... [more]
Cell Rep Dec. 26, 2019; 31(8);107693 [Pubmed: 32460013]
Throughput
- High Throughput
Curated By
- BioGRID