RPS0A
Gene Ontology Biological Process
- cytoplasmic translation [IMP]
- endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [IMP]
- endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [IMP]
- rRNA export from nucleus [IGI]
- ribosomal small subunit assembly [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
MTR4
Gene Ontology Biological Process
- U4 snRNA 3'-end processing [IMP]
- U5 snRNA 3'-end processing [IMP]
- exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [IMP]
- ncRNA polyadenylation [IDA]
- nuclear mRNA surveillance of mRNA 3'-end processing [IGI, IMP]
- nuclear polyadenylation-dependent mRNA catabolic process [IMP]
- nuclear polyadenylation-dependent rRNA catabolic process [IMP]
- nuclear polyadenylation-dependent tRNA catabolic process [IDA, IGI]
- nuclear retention of pre-mRNA with aberrant 3'-ends at the site of transcription [IGI]
- polyadenylation-dependent snoRNA 3'-end processing [IMP]
- rRNA catabolic process [IMP]
Gene Ontology Molecular Function
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Tsr4 and Nap1, two novel members of the ribosomal protein chaperOME.
Dedicated chaperones protect newly synthesized ribosomal proteins (r-proteins) from aggregation and accompany them on their way to assembly into nascent ribosomes. Currently, only nine of the ?80 eukaryotic r-proteins are known to be guarded by such chaperones. In search of new dedicated r-protein chaperones, we performed a tandem-affinity purification based screen and looked for factors co-enriched with individual small subunit ... [more]
Throughput
- High Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| MTR4 RPS0A | Negative Genetic Negative Genetic Mutations/deletions in separate genes, each of which alone causes a minimal phenotype, but when combined in the same cell results in a more severe fitness defect or lethality under a given condition. This term is reserved for high or low throughput studies with scores. | High | -0.1347 | BioGRID | 391164 | |
| RPS0A MTR4 | Negative Genetic Negative Genetic Mutations/deletions in separate genes, each of which alone causes a minimal phenotype, but when combined in the same cell results in a more severe fitness defect or lethality under a given condition. This term is reserved for high or low throughput studies with scores. | High | -0.2365 | BioGRID | 2046057 | |
| MTR4 RPS0A | Negative Genetic Negative Genetic Mutations/deletions in separate genes, each of which alone causes a minimal phenotype, but when combined in the same cell results in a more severe fitness defect or lethality under a given condition. This term is reserved for high or low throughput studies with scores. | High | -0.2035 | BioGRID | 1992167 |
Curated By
- BioGRID