COL2A1
Gene Ontology Biological Process
- axon guidance [TAS]
- cartilage development [TAS]
- collagen catabolic process [TAS]
- collagen fibril organization [IMP]
- embryonic skeletal joint morphogenesis [IMP]
- extracellular matrix disassembly [TAS]
- extracellular matrix organization [TAS]
- sensory perception of sound [IMP]
- skeletal system development [IMP]
- visual perception [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
ANXA5
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Reconstituted Complex
An interaction is inferred between proteins in vitro. This can include proteins in recombinant form or proteins isolated directly from cells with recombinant or purified bait. For example, GST pull-down assays where a GST-tagged protein is first isolated and then used to fish interactors from cell lysates are considered reconstituted complexes (e.g. PUBMED: 14657240, Fig. 4A or PUBMED: 14761940, Fig. 5). This can also include gel-shifts, surface plasmon resonance, isothermal titration calorimetry (ITC) and bio-layer interferometry (BLI) experiments. The bait-hit directionality may not be clear for 2 interacting proteins. In these cases the directionality is up to the discretion of the curator.
Publication
Selective binding of anchorin CII (annexin V) to type II and X collagen and to chondrocalcin (C-propeptide of type II collagen). Implications for anchoring function between matrix vesicles and matrix proteins.
Anchorin CII is a collagen binding protein of the annexin family associated with plasma membranes of chondrocytes, osteoblasts, and many other cells. As a major constituent of cartilage-derived matrix vesicles it has been shown to bind to native type II and X collagen. In accordance with this observation, here we show the localization of anchorin CII in the extracellular matrix ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID