Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Publication

PAPIN. A novel multiple PSD-95/Dlg-A/ZO-1 protein interacting with neural plakophilin-related armadillo repeat protein/delta-catenin and p0071.

Deguchi M, Iizuka T, Hata Y, Nishimura W, Hirao K, Yao I, Kawabe H, Takai Y

A neural plakophilin-related armadillo repeat protein (NPRAP)/delta-catenin interacts with one of Alzheimer disease-related gene products, presenilin 1. We have previously reported the interaction of NPRAP/delta-catenin with synaptic scaffolding molecule, which is involved in the assembly of synaptic components. NPRAP/delta-catenin also interacts with E-cadherin and beta-catenin and is implicated in the organization of cell-cell junctions. p0071, a ubiquitous isoform of NPRAP/delta-catenin, ... [more]

J. Biol. Chem. Sep. 22, 2000; 275(38);29875-80 [Pubmed: 10896674]

Throughput

Low Throughput

Related interactions

Interaction	Experimental Evidence Code	Dataset	Throughput	Score	Curated By	Notes
PDZD2 CTNND2	Reconstituted Complex Reconstituted Complex An interaction is detected between purified proteins in vitro.	Deguchi M (2000)	Low	-	BioGRID	-

Curated By

BioGRID

Interaction Summary

PDZD2

Gene Ontology Cellular Component

CTNND2

Gene Ontology Biological Process

Gene Ontology Molecular Function

protein binding [IPI]