BAIT
TRIM37
MUL, POB1, TEF3
tripartite motif containing 37
GO Process (6)
GO Function (5)
GO Component (4)
Gene Ontology Biological Process
- aggresome assembly [IDA]
- negative regulation of NF-kappaB transcription factor activity [IDA]
- negative regulation of centriole replication [IMP]
- positive regulation of NF-kappaB transcription factor activity [IDA]
- positive regulation of sequence-specific DNA binding transcription factor activity [IDA]
- protein autoubiquitination [IDA]
Gene Ontology Molecular Function
Homo sapiens
PREY
SAR1A
SAR1, SARA1, Sara, masra2, RP11-367H5.4
secretion associated, Ras related GTPase 1A
GO Process (0)
GO Function (0)
GO Component (1)
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
ROS/NF-?B Signaling Pathway-Mediated Transcriptional Activation of TRIM37 Promotes HBV-Associated Hepatic Fibrosis.
Hepatic fibrosis is an inflammatory response that leads to liver cirrhosis in the most advanced condition. Liver cirrhosis is a leading cause of deaths associated with liver diseases; hence, understanding the underlying mechanisms of hepatic fibrosis is critical to develop effective therapies. Tripartite motif (TRIM) family proteins have been shown to be involved in liver fibrosis; however, the exact role ... [more]
Mol Ther Nucleic Acids Aug. 19, 2020; 22();114-123 [Pubmed: 32916597]
Throughput
- High Throughput
Curated By
- BioGRID