BAIT

SPOP

BTBD32, TEF2
speckle-type POZ protein
GO Process (1)
GO Function (2)
GO Component (2)
Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

SPOP attenuates migration and invasion of choriocarcinoma cells by promoting DHX9 degradation.

Yuan D, Chen Y, Yang Z, Li G, Wu M, Jiang J, Li D, Yu Q

Speckle-type POZ protein (SPOP), a novel cancer- associated protein, was previously reported to function as a tumor suppressor or promoter in different malignant tumors. This research aims to investigate the biological functions and underlying molecular mechanisms of SPOP in choriocarcinoma. Our analysis of patient tissues and cell lines showed significantly decreased SPOP expression and highly expressed Nuclear DNA helicase II ... [more]

Am J Cancer Res Sep. 10, 2020; 10(8);2428-2445 [Pubmed: 32905556]

Throughput

  • High Throughput

Curated By

  • BioGRID