BAIT
NFYB
CBF-A, CBF-B, HAP3, NF-YB
nuclear transcription factor Y, beta
GO Process (3)
GO Function (4)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
CEBPZ
CBF, CBF2, HSP-CBF, NOC1
CCAAT/enhancer binding protein (C/EBP), zeta
GO Process (2)
GO Function (4)
GO Component (0)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
HSP-CBF is an NF-Y-dependent coactivator of the heat shock promoters CCAAT boxes.
The cellular response to toxic stimuli is elicited through the expression of heat shock proteins, a transcriptional process that relies upon conserved DNA elements in the promoters: the Heat Shock Elements, activated by the heat shock factors, and the CCAAT boxes. The identity of the CCAAT activator(s) is unclear because two distinct entities, NF-Y and HSP-CBF, have been implicated in ... [more]
J. Biol. Chem. Jul. 13, 2001; 276(28);26332-9 [Pubmed: 11306579]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| CEBPZ NFYB | Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation. | Low | - | BioGRID | - |
Curated By
- BioGRID