BAIT

UBE3C

HECTH2, tcag7.998
ubiquitin protein ligase E3C
GO Process (2)
GO Function (2)
GO Component (3)
Homo sapiens
PREY

RAD18

RNF73
RAD18 E3 ubiquitin protein ligase
GO Process (1)
GO Function (5)
GO Component (2)

Gene Ontology Biological Process

Gene Ontology Cellular Component

Homo sapiens

Affinity Capture-Western

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.

Publication

LINC00355 induces gastric cancer proliferation and invasion through promoting ubiquitination of P53.

Zhao W, Jin Y, Wu P, Yang J, Chen Y, Yang Q, Huo X, Li J, De W, Chen J, Yang F

Long noncoding RNAs (LncRNAs) have been reported to play critical roles in gastric cancer, but true biomarkers remain unknown. In this study, we found a new lncRNA LINC00355 that was involved in malignant progression of gastric cancer (GC) and further revealed its role and mechanism. Differentially expressed lncRNAs were identified through bioinformatics, and qRT-PCR was used to validate the expression ... [more]

Cell Death Discov Oct. 22, 2020; 6();99 [Pubmed: 33083020]

Throughput

  • Low Throughput

Curated By

  • BioGRID