CHML
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
RAB3A
Gene Ontology Biological Process
- GTP catabolic process [IDA]
- Rab protein signal transduction [IBA]
- constitutive secretory pathway [TAS]
- glutamate secretion [TAS]
- intracellular protein transport [IBA]
- neurotransmitter secretion [TAS]
- positive regulation of exocytosis [TAS]
- positive regulation of regulated secretory pathway [IMP]
- protein localization to plasma membrane [IBA]
- protein secretion [IBA]
- regulation of short-term neuronal synaptic plasticity [ISS]
- regulation of synaptic vesicle fusion to presynaptic membrane [ISS]
- synaptic transmission [TAS]
- synaptic vesicle exocytosis [ISS]
- synaptic vesicle recycling [ISS]
- vesicle docking involved in exocytosis [IBA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- axon [ISS]
- clathrin-sculpted acetylcholine transport vesicle membrane [TAS]
- clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane [TAS]
- clathrin-sculpted glutamate transport vesicle membrane [TAS]
- clathrin-sculpted monoamine transport vesicle membrane [TAS]
- endosome [IBA]
- plasma membrane [TAS]
- secretory granule membrane [IBA]
- synaptic vesicle [ISS]
- terminal bouton [ISS]
- vesicle [IDA]
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
REP-2, a Rab escort protein encoded by the choroideremia-like gene.
Rab escort proteins (REPs) bind to newly synthesized Rab proteins and remain bound during and after the attachment of a geranylgeranyl (GG) group by the catalytic component of the Rab GG transferase. Transfer of the GG group is absolutely dependent on the participation of a REP. REP-1, the first characterized REP, is produced by a gene on the X chromosome ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| RAB3A CHML | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 0.9999 | BioGRID | 1176046 | |
| RAB3A CHML | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 0.9995 | BioGRID | 2230598 | |
| RAB3A CHML | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 0.9996 | BioGRID | 3088515 |
Curated By
- BioGRID