BAIT
SHANK2
AUTS17, CORTBP1, CTTNBP1, ProSAP1, SHANK, SPANK-3
SH3 and multiple ankyrin repeat domains 2
GO Process (7)
GO Function (3)
GO Component (14)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- apical plasma membrane [ISS]
- brush border membrane [ISS]
- ciliary membrane [ISS]
- dendritic spine [ISS]
- growth cone [ISS]
- ionotropic glutamate receptor complex [ISS]
- neurofilament [ISS]
- neuron projection [ISS]
- neuronal cell body [ISS]
- photoreceptor inner segment [ISS]
- photoreceptor outer segment [ISS]
- plasma membrane [ISS]
- postsynaptic density [ISS]
- postsynaptic membrane [ISS]
Homo sapiens
PREY
DLGAP2
DAP2, SAPAP2
discs, large (Drosophila) homolog-associated protein 2
GO Process (1)
GO Function (1)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Proline-rich synapse-associated proteins ProSAP1 and ProSAP2 interact with synaptic proteins of the SAPAP/GKAP family.
We have recently isolated a novel proline-rich synapse-associated protein-1 (ProSAP1) that is highly enriched in postsynaptic density (PSD). A closely related multidomain protein, ProSAP2, shares a highly conserved PDZ (PSD-95/discs-large/ZO-1) domain (80% identity), a ppI domain that mediates the interaction with cortactin, and a C-terminal SAM (sterile alpha-motif) domain. In addition, ProSAP2 codes for five ankyrin repeats and a SH3 ... [more]
Biochem. Biophys. Res. Commun. Oct. 14, 1999; 264(1);247-52 [Pubmed: 10527873]
Throughput
- Low Throughput
Curated By
- BioGRID