PREY

ARP42

arp4, SPAC23D3.09
SWI/SNF and RSC complex subunit Arp42
Schizosaccharomyces pombe (972h)

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

Fission yeast SWI/SNF and RSC complexes show compositional and functional differences from budding yeast.

Monahan BJ, Villen J, Marguerat S, Baehler J, Gygi SP, Winston F

SWI/SNF chromatin-remodeling complexes have crucial roles in transcription and other chromatin-related processes. The analysis of the two members of this class in Saccharomyces cerevisiae, SWI/SNF and RSC, has heavily contributed to our understanding of these complexes. To understand the in vivo functions of SWI/SNF and RSC in an evolutionarily distant organism, we have characterized these complexes in Schizosaccharomyces pombe. Although ... [more]

Nat. Struct. Mol. Biol. Aug. 01, 2008; 15(8);873-80 [Pubmed: 18622392]

Throughput

  • Low Throughput

Related interactions

InteractionExperimental Evidence CodeDatasetThroughputScoreCurated ByNotes
ARP42 RSC1
Negative Genetic
Negative Genetic

Mutations/deletions in separate genes, each of which alone causes a minimal phenotype, but when combined in the same cell results in a more severe fitness defect or lethality under a given condition. This term is reserved for high or low throughput studies with scores.

High-14.2322BioGRID
525348

Curated By

  • BioGRID