BAIT

MPP6

PALS2, VAM-1, VAM1, p55T

membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)

GO Process (1)

GO Function (1)

GO Component (2)

Gene Ontology Biological Process

protein complex assembly [NAS]

Gene Ontology Molecular Function

protein binding [IPI]

Gene Ontology Cellular Component

extracellular vesicular exosome [IDA]

CRISPR Database VEGA OMIM HGNC Alliance of Genome Resources Entrez Gene RefSeq UniprotKB Ensembl HPRD

Homo sapiens

PREY

KNSTRN

C15orf23, SKAP, TRAF4AF1, HSD11

kinetochore-localized astrin/SPAG5 binding protein

GO Process (4)

GO Function (1)

GO Component (5)

Gene Ontology Biological Process

chromosome segregation [IMP]

mitotic sister chromatid segregation [IMP]

regulation of attachment of spindle microtubules to kinetochore [IMP]

spindle organization [IMP]

Gene Ontology Molecular Function

protein binding [IPI]

Gene Ontology Cellular Component

cytoplasm [IDA]

kinetochore [IDA]

microtubule cytoskeleton [IDA]

microtubule plus-end [IDA]

mitotic spindle [IDA]

CRISPR Database VEGA HGNC Alliance of Genome Resources OMIM Entrez Gene RefSeq UniprotKB Ensembl HPRD

Homo sapiens

Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Publication

A protein interaction framework for human mRNA degradation.

Lehner B, Sanderson CM

The degradation of mRNA is an important regulatory step in the control of gene expression. However, mammalian RNA decay pathways remain poorly characterized. To provide a framework for studying mammalian RNA decay, a two-hybrid protein interaction map was generated using 54 constructs from 38 human proteins predicted to function in mRNA decay. The results provide evidence for interactions between many ... [more]

Genome Res. Jul. 01, 2004; 14(7);1315-23 [Pubmed: 15231747]

Throughput

High Throughput

Curated By

BioGRID