BAIT
MPP6
PALS2, VAM-1, VAM1, p55T
membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
GO Process (1)
GO Function (1)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
AATF
BFR2, CHE-1, CHE1, DED, HSPC277
apoptosis antagonizing transcription factor
GO Process (8)
GO Function (4)
GO Component (5)
Gene Ontology Biological Process
- apoptotic signaling pathway [TAS]
- cellular response to DNA damage stimulus [IEP]
- negative regulation of apoptotic process [IMP]
- negative regulation of reactive oxygen species metabolic process [IDA]
- negative regulation of superoxide anion generation [IDA]
- neurotrophin TRK receptor signaling pathway [TAS]
- positive regulation of apoptotic process [TAS]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A protein interaction framework for human mRNA degradation.
The degradation of mRNA is an important regulatory step in the control of gene expression. However, mammalian RNA decay pathways remain poorly characterized. To provide a framework for studying mammalian RNA decay, a two-hybrid protein interaction map was generated using 54 constructs from 38 human proteins predicted to function in mRNA decay. The results provide evidence for interactions between many ... [more]
Genome Res. Jul. 01, 2004; 14(7);1315-23 [Pubmed: 15231747]
Throughput
- High Throughput
Curated By
- BioGRID